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About


REvolutionizing the Assessment of the toxicity of pesticides on Soil microorganisms: from Single species tests to EcoSystem approacheS.

Pesticides constitute major environmental pollutants. In order to protect the environment and human health the European Commission (EC) has imposed a stringent regulatory scheme for pesticides (Regulation 1107/2009). The frame risk assessment of aquatic organisms and terrestrial macro-organisms has been thoroughly investigated, although the toxicity assessment of pesticides on soil microorganisms is lagging behind. In 2010 the European Food Safety Authority (EFSA) identified soil microorganisms as an attribute to monitor in pesticides environmental risk assessment, due to their fundamental role in soil ecosystem functioning. In 2017 EFSA reinforced the need for establishing novel tests and procedures to assess pesticides toxicity on soil microorganisms. Previous research conducted by the University of Thessaly (UTH) and EFSA scientific opinion has pointed to AOM (Ammonia Oxidizing Microorganisms) including ammonia-oxidizing bacteria (AOB), ammonia-oxidizing archaea (AOA) and nitrite oxidizing bacteria (NOB), as well as AMF (Arbuscular Mycorrhizal Fungi) as ideal microbial indicators of pesticides toxicity, due to their contribution in soil viability.
The project ReASSESS timely comes to fulfil this scientific and regulatory gap through an exclusive research program aiming to produce the benchmarking knowledge required to comprehensively assess the soil microbial toxicity of pesticides. In this quest novel tools, experimental procedures and risk assessment schemes will be developed in order to provide fundamental scientific knowledge and eventually reform the currently outdated pesticide risk assessment framework.


Aim
The main research queries will be addressed through 3 main research objectives:
- Tier I (conservative step): develop and standardize pioneering single organisms in vitro teststo assess the toxicity of pesticides on phylogenetically and ecophysiologically distinct soil AOM and AMF.
- Tier II & III (realistic assessment step): develop and implement advanced experimental single group organisms in lab and field tests to assess pesticides toxicity on natural soil assemblages of AOM and AMF.
- Higher Tier (ecosystem functioning): develop in vitro and natural soil assemblages including microorganisms from different trophic-levels (AOM, protists) to assess the ecosystem-level assessment of pesticides toxicity within the soil food-web (predator - prey).

Research group


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Dimitrios G. Karpouzas (project role: Principal Investigator) is one of the leaders of Plant and Environmental Biotechnology (PEB) and Director of Department of Biochemistry and Biotechnology (DBB) of the University of Thessaly (UTh), and Soil Microbial Ecology and pesticides environmental fate and biodegradation expert.

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Evangelia Papadopoulou (project role: Host Institute PI) is an Assistant Professor in the Department of Environmental Science (DES) of the University of Thessaly. Her research interest is on effects of agrochemicals and agricultural practices on the function and structure of soil microbial communities, with the main focus on the biochemistry, ecology and function on N cycling microbes.

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Sotirios Vasileiadis (project role: Advisory Board Member) has recently become an Assistant Professor (in May 2021) at the group of Plant and Environmental Biotechnology (PEB), of the department of Biochemistry and Biotechnology (DBB), of the University of Thessaly (UTh), with expertise in Microbial Ecology, Meta-omics and associated bioinformatics. 

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Maria Papadatou (project role: Postdoctoral researcher) is a Postdoctoral researcher in DBB (Uth) in environmental and microbial biotechnology. Her research interests lie on the response of microbial fouling (biofouling) on antifouling applications, microbe-driven marine carbon cycling and ecosystem-level assessment of pesticides toxicity on soil microorganisms. In ReASSESS project she is working on the assessment of pesticides toxicity on microorganisms from different trophic-levels within the soil food-web (predator – prey).

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Maria Kolovou (project role: PhD student) is a Ph.D student in DES (UTh) in environmental and microbial biotechnology. In ReASSESS project she is working on pesticides toxicity assessment on ammonia oxidizing microorganisms, under Assist. Prof E. Papapdopoulou supervision.

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Christos Papadopoulos (project role: PhD Candidate) is a Ph.D student in DBB (UTh) in environmental and microbial biotechnology. In ReASSESS project he is working on pesticides toxicity assessment on arbuscular mycorrhizal fungi, under Prof D. Karpouzas supervision.

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Kalliope K Papadopoulou (project role: Advisory Board member) is a Professor in the DBB (Uth). She is one of the leaders of PEB group. Her main research interests are in plant specialized metabolism (biosynthesis, production in heterologous systems, biological activities) and in plant-microbe interactions, with emphasis on endophytic fungi, symbiotic relationships and multi-partite interactions.

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Prof. Stephane Declerck (UC Leuven, Belgium) is the head of the Mycology Laboratory in UCL, the host of GINCO, the largest world collection of AMF cultured in vitro. His group are global pioneers of the in vitro cultivation of AMF being able to cultivate about 20 phylogenetically and ecophysiological different AMF strains.

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Graeme W Nicol (project role: Advisory Board member) is CNRS senior researcher working in Ecole Centrale de Lyone, France. His research interests are focused on soil microbiology, in particular understanding the contribution of archaea and bacteria to the soil nitrogen cycle through both cultivation and molecular approaches.

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Prof Antonis Chatzinotas (UFZ, Germany) is a Professor in the University of Leipzig and leader of the group of Microbial Interaction Ecology in UFZ. He has strong expertise (i) in molecular microbial ecology in natural and engineered systems and (ii) in the use of assembled lab systems to study the role of biodiversity and microbial interactions within and across trophic levels.

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Constantinos Ehaliotis is Professor at the Agricultural University of Athens (AUA) and Soil Microbial Ecology and soil fertility expert

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Urania Menkissoglu-Spiroudi (project role: Advisory Board member) is the director of the pesticides laboratory of the Agricultural Sciences Faculty of the Aristotle University of Thassaloniki (AUTh) with extensive expertise in Analytical Agricultural Chemistry

Dissemination & Outreach



15-18/11/2022 Ecotoxicomic at Montpellier, France

Maria Kolovou along with Prof. Dimitrios Karpouzas presented her work in the frame of the project ReAssess at the ECOTOXICOMIC 2022 conference related to Microbial Ecotoxicology, in Montpellier. It was an excellent opportunity to network and connect with fellow scientists, foster new collaborations, and build lasting friendships.


26-30/06/2023 BAGECO at Copenhagen, Denmark

At the 16th Symposium on Bacterial Genetics and Ecology (BAGECO 2023) in Copenhagen, Maria Kolovou presented her research on "Development of in vitro bioassays for assessing pesticides toxicity on soil nitrifying microorganisms". Additionally, Maria awarded with the third price in the category of BEST POSTER. Congratulations!! Wishing you even more success in the future.

Keep in touch through our site for Dissemination & Outreach updates!

Contact us


Feel free to contact us at the following addresses:
- Prof. Dimitrios Karpouzas: dkarpouzas(at)uth.gr
- Dr. Evangelia Papadopoulou: evapapadopoulou(at)uth.gr
- Project email: reassess.h.f.r.i(at)gmail.com

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